Enzyme+-+bioregulation

**Pennsylvania Assessment (Eligible Content): ** **Anchor: ** **BIO.A.2.3 ** Describe how enzymes regulate biochemical reactions within a cell.
 * Title:** //Enzymes / Chemical Basis of Life (BioA.2)//
 * grade level:** 10
 * Subject Area:** //Accelerated Biology//
 * Designers**: Cinda Murray **frame**: 2 weeks

**BIO.A.2.3.1** Describe the role of an enzyme as a catalyst in regulating a specific biochemical reaction.
 * Eligible Comtent: **
 * BIO.A.2.3.2** Explain how factors such as pH, temperature, and concentration levels can affect enzyme function.

3.1.B.A2 & 3.1.B.A7
 * Science Standards:**

 This unit will examine the biochemical regulation of processes in cells contributing to maintaining life and more specifically homeostasis.
 * Theme / “Big Idea” **:

**Essential Questions **:
 * 1) How do living things regulate cell processes?
 * 2) How do enzymes work?
 * 3) What factors affect enzyme activity?
 * 4)  Explain the lock and key theory, and why it is not a perfect model?

pH acid base macromolecule protein catalyst enzyme denatured substrate enzyme -substrate complex
 * Key Vocabulary:**

**Performance Indicators / Objectives **<span style="font-family: 'Arial','sans-serif';">:
 * <span style="font-family: 'Arial','sans-serif';">Organize, record, graph, and analyze data
 * <span style="font-family: 'Arial','sans-serif';">Practice safe laboratory techniques
 * <span style="font-family: 'Arial','sans-serif';">Distinguish enzyme, substrate, and enzyme-substrate complex
 * <span style="font-family: 'Arial','sans-serif';">Use lab techniques to evaluate the effects of temperature, pH, and concentration on enzyme activity.

**<span style="font-family: 'Arial','sans-serif';">Performance tasks: ** <span style="display: block; font-family: 'Arial','sans-serif'; margin: 0in 0in 0pt;"> Graded notebooks- bell ringers, journal entries Lab activity- macromolecule ID Lab activity- Indicators for macromoleculesWorksheets- guided reading Quizzes Tests – written Homework **<span style="font-family: 'Arial','sans-serif';">Writing: **<span style="font-family: 'Arial','sans-serif';">Note-taking Summarizing / reflections Research paper Descriptive writing Lab reports **<span style="font-family: 'Arial','sans-serif';">Thinking: **<span style="font-family: 'Arial','sans-serif';">Analyzing Evaluating Compare / Contrast Synthesizing **<span style="font-family: 'Arial','sans-serif';">Speaking: ** <span style="display: block; font-family: 'Arial','sans-serif';">Small group discussions Class discussions **<span style="font-family: 'Arial','sans-serif';">Reading: ** <span style="display: block; font-family: 'Arial','sans-serif';">Graphic organizers Outlining / notetaking, Popcorn / Spirit reading

<span style="display: block; font-family: 'Arial','sans-serif';"> Lecture & discussion, Lab Activity, Computer simulations, VCR/DVD, Smart board, Guided practice, Bell ringers, Cooperative learning
 * <span style="display: block; font-family: 'Arial','sans-serif';">Teaching strategies: **

<span style="display: block; font-family: 'Arial','sans-serif';"> Differentiated materials as needed; Extra time provided after school (help sessions)
 * <span style="display: block; font-family: 'Arial','sans-serif';">Adaptations: **

<span style="display: block; font-family: 'Arial','sans-serif';">Why is regulation of a system important?
 * <span style="display: block; font-family: 'Arial','sans-serif';">Open ended Question: **